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  5. 1-(5-Bromo-2-hydroxy-4-methoxyphenyl)ethanone [SE1] inhibits MMP-9 expression by regulating NF-κB an

1-(5-Bromo-2-hydroxy-4-methoxyphenyl)ethanone [SE1] inhibits MMP-9 expression by regulating NF-κB an

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：zhizu81748
【摘 要】
：
Hippocampus is a traditional medicine in China,which can be used for treating tumors,aging,fatigue,thrombosis,inflammation,hypertension,prostatic hyperplasia and other diseases.1-(5-Bromo-2-hydroxy-4-
【作 者】
：
Fang Gong YuanYuan Zhang JiaChao Lin ChengYong Li ChunXia Zhou PengZhi Hong BoMi Ryu Zhong-Ji Qian 
【机 构】
：
College of Food Science and Technology,Guangdong Ocean University,Zhanjiang 524088
【出 处】
：
中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议
【发表日期】
：
2018年10期
【关键词】
：
Hippocampus SE1 Anti-metastatic MMP-9 MAPKs NF-κB molecular docking 
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　　Hippocampus is a traditional medicine in China,which can be used for treating tumors,aging,fatigue,thrombosis,inflammation,hypertension,prostatic hyperplasia and other diseases.1-(5-Bromo-2-hydroxy-4-methoxyphenyl)ethanone [SE1] from seahorse(Hippocampus kuda Bleeler)has been shown to suppress pro-inflammatory responses.In present study,SE1 potently inhibited gelatin digestion by MMP-9 induced by phorbol 12-myristate 13-acetate(PMA)and migration of human fibrosarcoma HT1080 cells in dose dependently.
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