The platinum cellular uptake as biomarker for uterine cervix carcinoma therapy

来源 :The 5th International Symposium on Metallomics(第五届金属组学国际研讨会) | 被引量 : 0次 | 上传用户：lingang89029

【摘要】

：

　　The uterine cervix carcinoma is one of the malignant diseases where platinum-based drugs such cisplatin are included in the standard radio-chemotherapy(RT)p

【作者】

：

EvaFischer-Fodor[1]PetruIlea[2]IoanaCarmenBrie[3]PiroskaVirag[1]CorinaTatomir[1]FloricaImre-Lucaci[2]GabrielaChereches[1]LuminitaSilaghiDumitrescu[4]VioricaMagdalenaNagy[3]

【机构】

：

Research Department,Institute of Oncology “I.Chiricuta”,Cluj Napoca,RO-400015,Romania

【出处】

：

The 5th International Symposium on Metallomics(第五届金属组学国际研讨会)

【发表日期】

：

2015年期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　The uterine cervix carcinoma is one of the malignant diseases where platinum-based drugs such cisplatin are included in the standard radio-chemotherapy(RT)protocols and it is the basic component of the recently applied neoadjuvant therapy in this cancer type.

其他文献

Applications of Synchrotron Radiation Techniques in Studying Cytotoxicity of Silver Nanoparticles

　　To predict potential medical value or toxicity of nanoparticles(NPs),it is necessary to understand the chemical transformation during intracellular processe

会议

Potential Roles of Selenoprotein and Se-containing compounds in the Intervention of Alzheimer's

　　Alzheimer's disease is a devastating and invariably fatal neurodegenerative brain disorder with no cure.

会议

Ruthenium(Ⅱ)complexes as fluorescence probe in imaging living cell

　　For years ruthenium(Ⅱ)complexes have been proposed as useful fluorophores for cell imaging ascribe to their attractive photophysical properties [1-6](Fig.1

会议

The Accumulation and Metabolism features of Rare Earth Elements La,Ce,Pr,Nd,Gd in Tissues and Organs

　　Objective: To investigate the influence of rare earth elements(REEs)La,Ce,Pr,Nd,Gd to the growth of SD rats,explore the accumulation features of them in dif

会议

The chelating properties of the N-terminal domain of hCTR1

　　In cells,copper ions outside of the pre-organized coordination sphere of the cuproenzymes or copper transporting proteins catalyze the formation of ROS(Fent

会议

Crystallographic studies on the interaction between proteins and platinum-based drugs

　　Interactions of the Pt-based drugs with proteins play crucial roles in their uptake and biodistribution,as well as in determining their side effects,resista

会议

Exploration of zinc-responsive genes and metabolites responsible for stress tolerance of Saccharomyc

　　Saccharomyces cerevisiae strains are exposed to various stressful conditions during biofuels production,which include the toxic level of ethanol and inhibit

会议

The Variation of Hydroxyl Groups on the Flavonoid Backbone Directs the Modulation of Cu(Ⅱ)-Aβ Aggreg

　　Amyloid-β(Aβ)and transition metal ions have been suggested to be involved in the pathogenesis of Alzheimer's disease(AD).

会议

The functions of a His-rich metalloprotein Hpn in Helicobacter pylori

　　Helicobacter pylori(H.pylori)is a gram-negative bacterium causing gastritis,peptic ulcerations and gastric carcinoma [1].H.pylori produces a small cytoplasm

会议

The Association of depressed angiogenic factors with reduced capillary density in Rhesus monkey mode

　　Depressed capillary density is associated with myocardial ischemic infarction,in which hypoxia-inducible factor 1α(HIF-1α)is increased.

会议

The platinum cellular uptake as biomarker for uterine cervix carcinoma therapy

与本文相关的学术论文