No association between the FXYD6 gene and schizophrenia in the Chinese Han Population

来源 :第八次全国医学遗传学学术会议(中华医学会2009年医学遗传学年会) | 被引量 : 0次 | 上传用户:feixubushi
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  Choudhury et al.identified FXYD6 as a susceptible gene for schizophrenia in the London and Aberdeen populations.We genotyped D1 1S1998 and 8 SNPs (rs869789, rs11216567, rs10790212, rs876797, rs4938445, rs497768, rs11216598, rs11605223) in a Chinese sample consisting of 1514 schizophrenia patients and 1514 healthy controls.We also compared the expression levels of FXYD6 in lymphocytes in 86 schizophrenia patients and 94 controls.No association was detected either in D11S1998 or the 8 SNPs.No difference was found in expression level between patients and controls.Our study suggests that FXYD6 does not play a role in schizophrenia in the Chinese Han population.
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