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  5. Pinocembrin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum

Pinocembrin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：gaibian000000
【摘 要】
：
Aim: Endoplasmic reticulum stress (ER stress) is known to play a vital role in mediating ischemic reperfusion damage in brain.In this study an attempt was made to investigate the modulatory effect on
【作 者】
：
Cai-xia WU Rui LIU Mei GAO Gang ZHAO Song WU Chun-fu WU Guan-hua DU 
【机 构】
：
School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, Ch
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
endoplasmic reticulum stress focal cerebral ischemia reperfusion pinocembrin 
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Aim: Endoplasmic reticulum stress (ER stress) is known to play a vital role in mediating ischemic reperfusion damage in brain.In this study an attempt was made to investigate the modulatory effect on ischemia/reperfusion-induced ER stress of pinocembrin.Methods: Focal cerebral ischemia/reperfusion was induced by middle cerebral artery occlusion (MCAO) for 2 h followed by 6 h reperfusion.
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