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  5. Gel-Filter System for the Enrichment Of Low-Molecular Weight Proteins from Serum and Comparative Stu

Gel-Filter System for the Enrichment Of Low-Molecular Weight Proteins from Serum and Comparative Stu

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：cpingpeng
【摘 要】
：
The human serum proteome has been extensively studied to find protein and peptide biomarkers.Due to the large dynamic range of protein amounts in serum and especially several kinds of highly abundant
【作 者】
：
Lingsheng Chen Linhui Zhai Ning Li Lingyan Ping Chengpu Zhang Lei Chang Junzhu Wu Xiangping Li Deshun Shi Ping Xu 
【机 构】
：
State Key Laboratory of Proteomics,National Engineering Research Center for Protein Drugs,Beijing Pr
【出 处】
：
第八届中国蛋白质组学大会
【发表日期】
：
2013年11期
【关键词】
：
Serum Gel-filter Low-molecular weight protein Mass spectrometry 
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The human serum proteome has been extensively studied to find protein and peptide biomarkers.Due to the large dynamic range of protein amounts in serum and especially several kinds of highly abundant and large molecular weight proteins,identifying and detecting amount changes in small molecular weight but physiologically and pathologically informative proteins (molecular weight ≤30kDa) and peptides by varied enrichmental methods and mass spectrometry analysis are constrained.
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