【摘 要】
：
Dental resins containing 12-methaeryloyloxydodecylpyridinium bromide (MDPB) showed potent antibacterial functions.Recent studies developed antibacterial resins containing nanoparticles of silver (NAg)
【机 构】
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Biomaterials & Tissue Engineering Division, Department of Endodontics, Prosthodontics and Operative
【出 处】
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首都医科大学2013年研究生学术论坛
论文部分内容阅读
Dental resins containing 12-methaeryloyloxydodecylpyridinium bromide (MDPB) showed potent antibacterial functions.Recent studies developed antibacterial resins containing nanoparticles of silver (NAg).The objectives of this study were to develop an adhesive containing dual agents of MDPB and NAg for the first time and to investigate the combined effects of antibacterial adhesive and primer on biofilm viability, metabolic activity, lactic acid, dentin bond strength, and fibroblast cytotoxicity.MDPB and NAg were incorporated into Scotchbond Multi-Purpose (SBMP) adhesive "A" and primer "P".Five systems were tested: SBMP adhesive A;A (b) MDPB;A(b)NAg;A (b) MDPB (b) NAg;P (b) MDPB (b) NAg together with A (b) MDPB (b) NAg.Dental plaque microcosm biofilms were cultured using mixed saliva from 10 donors.Metabolic activity, colony-forming units, and lactic acid production of biofilms were investigated.Human fibroblast cytotoxicity of bonding agents was determined.MDPB (b) NAg in adhesive/primer did not compromise dentin bond strength (p > 0.1).MDPB or NAg alone in adhesive substantially reduced
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