Vitamin C enhances tet-mediated 5-methylcytosine oxidation as a cofactor and promotes DNA demethylat

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户:and113
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DNA demethylation remarkably contributes to the dynamics of the epigenetic marker 5-methylcytosine (5mC) in mammals, and is critical for multiple biological processes, including animal cloning, nuclear reprogramming,development, and highly locus-specific regulation of gene activities.
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