Aluminium (Al) distributes widespread throughout nature and the main route of Al input to human is through foods,drinking waters and cooking utensils.Due to the wide occurrence of Al exposed to human beings,it can lead to some diseases[1,2].Determine ultra–trace Al(Ⅲ) has become very important and the commonly used methods are spectroscopic techniques,including AAS[3],UV–Vis[4],and fluorescence[5].However,these methods often need separation and preconcentration steps.Flow injection–chemiluminescence (FI–CL) method is an interesting option without any pretreatment proceduce and has advantages over other techniques.Based on the enhancing effect of Al(Ⅲ) on the luminol–dissolved oxygen reaction,a novel rapidity,sensitivity and simplicity FI-CL method was developed for the determination of Al(Ⅲ).It was found that the maximum CL instensity could be obtained when using a concentration of 2.5×10–5 mol/L luminol and 0.025 mol/L NaOH.The increment CL intensity was proportional to the concentration of Al(Ⅲ) over the range from 19.0 pg/mL to 2.7 ng/mL,and the regression equation was ΔI CL = 0.11 CAl(Ⅲ) + 7.87,R2 = 0.9956,with the detection limit of 6.0 pg/mL (3σ).At a flow rate of 2.0 mL/min,one analysis cycle,including sampling and washing,could be accomplished in 0.5 min.The proposed method was applied successfully in determining of Al(Ⅲ) content in Compound Aluminium Hydroxide Tablets with recoveries from 96.5 to 107.7%,and the relative standard deviations of less than 3.0% (n = 5).