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Livin is a new and important member of the inhibitor of apoptosis protein (IAPs) family.Livin is high expressed in most human tumor cells, involved in apoptosis inhibition and closely related with tumor development and progression.Livin controls cell apoptosis in many species through restrains caspase.In recent years, Livin was found specificity expression in esophageal carcinoma cells.The tumor cells could be inhibited or killed by the antibody expression or inhibition of Livin gene.It could be provides a novel strategy for esophageal carcinoma diagnossis and genes therapy.