Simultaneous determination of four tobacco-specific N-nitrosamines based on liquid-liquid extraction

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Tobacco-specific N-nitrosamines (TSNAs),including N-nitrosonornicotine (NNN),4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK),N-nitrosoanatabine (NAT),and N-nitrosoanabasine (NAB),have been implicated as a source of carcinogenicity in tobacco and cigarette smoke.
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