Parkinsons disease(PD)is a common neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra(SN)and the appearance of fibrillar aggregates of α-synuclein calle
Spinocerebellar ataxia type 3/Machado-Joseph disease(SCA3/MJD)is the most common subtypes of spinocerebellar ataxias in China,which belong to the polyglutamine diseases.
Objective:To optimize the conditions of transfecting eukaryotic expression vector pEGFP-N1 into neural stem cells(NSCs)from rats by CUY21EDITII electroporator,in order to improve the transfection effi
Objective: Alzheimers disease(AD)is a neurodegenerative disease.The two obvious neuropatholopgical changes in AD are senile plaques(SP)and neurofibrillary tangles(NFT).
Early,reliable and non-invasive diagnosis of Alzheimer disease(AD)is a great challenge,which makes the prognosis and therapeutic interventions quite difficult.
Parkinsons disease(PD)is a progressive neurodegenerative movement disorder that is caused predominantly by the degeneration of the nigrostriatal dopaminergic pathway.