【摘 要】
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We have recently demonstrated that, in breast cancer, mammary adipocytes participate in a highly complex vicious cycle orchestrated by cancer cells to support tumor progression.Peri-tumoral adipocytes
【机 构】
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Institut de Pharmacologie et de Biologie Structurale,CNRS UMR 5089,Toulouse,France;INSERM UMR 1048,I
【出 处】
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第六届/中-法(国际)乳腺癌高级学术论坛
论文部分内容阅读
We have recently demonstrated that, in breast cancer, mammary adipocytes participate in a highly complex vicious cycle orchestrated by cancer cells to support tumor progression.Peri-tumoral adipocytes exhibit modified phenotype and specific biological features (we named these adipocytes 《Cancer-Associated Adipocytes,CAAs) and strongly stimulate breast cancer invasion in vitro and in vivo (Dirat et al, Cancer Res 2011 71:2455-2465).
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