Tumor MET Expression by Immunohistochemistry (IHC) in Chinese Patients With Advanced Gastric or Gast

来源 :第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 | 被引量 : 0次 | 上传用户:gwxy110
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Objective: Gastric cancer accounts for >325,000 deaths in China annually.The MET receptor and its ligand hepatocyte growth factor are promising targets in G/GEJ cancer.Our objective was to evaluate overall survival (OS) by tumor MET expression and by treatment disposition in Chinese patients with advanced G/GEJ cancer.
其他文献
Objective: To observe the protective effect and the underlying mechanism of total ginsenosides on bleomycin-induced pulmonary fibrosis.
Objective: To investigate the effects of icariin Ⅱ (IRS) on myocardial fibrosis in spontaneously hypertensive rats (SHR), and to explore the mechanisms.Methods: 14-week-old male SHRs were randomly div
Parkinsons disease (PD) is a neurodegenerative disease characterized by a slow and progressive loss of dopamine (DA) neurons in the substantia nigra (SN).Neuroinflammation, an important contributor to
CX3CL1 is closely related with vascular inflammatory diseases, upregulation of CX3CL1 byactivation of NF-κB signaling pathway promote migration and adhesion of inflammatory cells tovascular wall leadi
Objective: To investigate the effects of icariin (ICA) on migration and adhesion of human acute monocytic leukemia cell line (THP-1) to human umbilical vein endothelial cells (HUVECs) induced by tumor
法尼醇X受体(farnesoidXreceptor,FXR)是属于核受体超家族的一类配体激活型转录因子.FXR在胆汁酸、肥胖和糖类代谢的基因调控中具有重要作用[1].经研究发现抗炎作用也是FXR的一项重要的功能,下面对其抗炎机制的研究作简要综述:1..配体激活FXR后可以抑制核转录因子NF-kB引起的炎症因子的表达,证明了FXR在肝炎反应中起负调节作用[2].Ingrid T.G.W.Bijsma
背景:LOX-1是表达于内皮细胞膜上的ox-LDL的主要受体,在动脉粥样硬化(atherosclerosis,AS)发生、发展过程中起重要作用.二氢丹参酮Ⅰ (DHT)是传统中药丹参的脂溶性成分之一.本研究探讨其对LOX-1表达的调控及对AS的改善作用.
目的:雄黄配伍中药或西药均能增强抗肿瘤药物的药效.但雄黄水溶性低,而雄黄量子点(Realgar Quantum Dots,RQDs)易溶,且有较强的抗肿瘤活性.本实验研究了RQDs抑制子宫内膜癌JEC细胞的增殖及与自噬的关系.方法:透射电镜观察RQDs作用于JEC细胞后自噬体的产生;共聚焦显微镜观察JEC细胞转染质粒p-EGFP-C3-LC3B后的荧光变化;Western Blot检测自噬相关蛋白
目的:70味珍珠丸是珍宝类藏药,由金、银、珍珠、珊瑚、麝香、牛黄、藏红花等70余味动物、植物和矿物药组成,主要用于心血管系统疾病,因其保肝作用尚未见报道,所以本实验研究其对四氯化碳致急性肝损伤小鼠的保护作用.
目的:探讨人参茎叶总皂苷(TG)对小鼠肺间质纤维化的保护作用,并初步探讨其作用机制.方法: 60只昆明种小鼠随机分为假手术组、模型组、TG40,80和160mg·kg-1组及阳性药醋酸泼尼松5mg·kg-1组.气管内灌注博来霉素5mg·kg-1建立肺纤维化小鼠模型.制模次日灌胃给药,每天1次,连续28天,计算小鼠肺系数、HE染色及Masson染色观察肺组织病理形态改变、Real Time PCR法