GINSENOSIDE RB1 PROTECTS HUVECs SURVIVE BY UP REGULATING AND ACTIVATING SPECIFIC GHRELIN RECEPTOR

来源 :第九届海峡两岸心血管科学研讨会暨首届台湾南部国际心脑血管科学研讨会 | 被引量 : 0次 | 上传用户:xiezhen120
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Studies have indicated that both ginsenoside Rbl and ghrelin could prevent homocysteine (Hcy)-induced endothelial dysfunction through eNOS/NO mechanism.Our study showed that endogenous ghrelin mediates the endothelial protection of ginsenoside Rb1 through in vitro and in vivo experiments, in addition, ginsenoside Rbl upregulates NO signaling pathway reduced by Hcy via ghrelin receptor GHSR-1a.
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