2. 您的位置
3. 首页
4. 会议论文
5. Statistical Inference for Chromatin 3D Structure

Statistical Inference for Chromatin 3D Structure

来源 :上海交通大学 | 被引量 : 0次 | 上传用户：ziyutianxia

【摘 要】

：

The expression of a gene is usually controlled by the regulatory elements in its promoter region.However,it has long been hypothesized that,in complex genomes,such as the human genome,a gene may be co

【作 者】

：

Shili Lin 

【机 构】

：

Department of Statistics,The Ohio State University,Columbus,OH 43210,USA

【出 处】

：

上海交通大学

【发表日期】

：

2016年4期

【关键词】

：

chromatin organization spatial interaction dependency over-dispersion data resol 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　The expression of a gene is usually controlled by the regulatory elements in its promoter region.However,it has long been hypothesized that,in complex genomes,such as the human genome,a gene may be controlled by distant enhancers and repressors.

其他文献

MRCTs for China Submission-Practice,Challenge and Future direction

Global submission with data from MRCTs is a normal practice,particularly for big outcome studies,rare disease,or disease with high unmet medical need etc.

会议

MRCTglobal drug developmentNDA submission in China

Composite Designs Based on Orthogonal Arrays and Definitive Screening Designs

Central composite designs are widely used in practice for factor screening and building response surface models.

会议

Central composite designconference matrixD-efficiencydefinitive screening des

Optimal Two-Stage Adaptive Enrichment Designs,using Sparse Linear Programming

We propose new,optimal methods for analyzing randomized trials,when it is suspected that treatment effects may differ in two predefined subpopulations.

会议

Treatment Effect HeterogeneityMultiple Testing Procedure

RegODA:Univariate Regression Modeling for the Orthogonal Decomposition Analysis of Multiple Correlat

Multiple correlated phenotypes are frequently collected in genome-wide association studies(GWASs),and a systematic,simultaneous analysis of multiple phenotypes can integrate the signals from single ph

会议

GWASMultiple Correlated PhenotypesSummary Data

Statistical Approaches to Estimating the Number of Signal Sources in Magnetoencephalography

Magnetoencephalography(MEG)is an imaging technique used to measure the magnetic field outside the human head produced by the electrical activity inside the brain.

会议

brain imaginginverse MEG problemspiked eigenvalueintrinsic dimensionalityeig

New Semiparametric Estimation Procedure for Functional Coefficient Longitudinal Data Models

In order to achieve dimension reduction for the nonparametric functional coefficients and improve the estimation efficiency,in this paper we introduce a novel semiparametric estimation procedure which

会议

Cholesky decompositionfunctional coefficientslocal linear smoothingprincipal

Sliced rotated sphere packing designs

Space-filling designs are popular choices for computer experiments.A sliced design is a design that can be partitioned into several subdesigns.

会议

Design of experimentExpected improvementMaximin distanceNested designSe-quen

On Asymptotic Optimality of the Cross-Validation Selected Bandwidth for Complex Spatial Data:Case of

Spatial kernel estimate or smoothing has become a useful tool in exploring non-Gaussian distributions for complex spatial data,collected with modern data acquisition techniques.

会议

Asymptotic optimalitybandwidth selectionkernel and adaptive kernel density est

Mixture-of-experts models with diverging number of parameters

Recent advancements in medical and other fields of scientific research have allowed scientists to collect data of unprecedented size and complexity.

会议

Mixture modelsEM algorithmRegularization

ADJUSTING FOR INCOMPLETE DEATH ASCERTAINMENT IN JOINT MODELS:A MULTIPLE-IMPUTATION APPROACH

Monitoring and evaluation of the effectiveness of HIV treatment programs involves estimating precisely the clinical outcome of their clients.

会议

Joint modelsmultiple imputationunknown death ascertainment