【摘 要】
：
Due to their remarkable stability and biocompatibility,high drug loading efficiency,and easy surface modification,mesoporous silica nanoparticles(MSNs)have emerged as attractive drug delivery vehicles
【机 构】
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School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China
【出 处】
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中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议
论文部分内容阅读
Due to their remarkable stability and biocompatibility,high drug loading efficiency,and easy surface modification,mesoporous silica nanoparticles(MSNs)have emerged as attractive drug delivery vehicles.However,for unmodified MSN-based nanocarriers,their applications were limited by the initially burst prerelease and serious leakage of physically loaded drug molecules during the blood circulation(1).Thus,various components,such as inorganic nanoparticles,polymers,supramolecular assemblies as gatekeepers,have been employed to construct end-capped MSNs in order to achieve the desired "zero premature drug release"(1).
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