【摘 要】
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Background and Aims: Immune thrombocytopenia (ITP) is an autoimmune disorder.Dysfunction of dendritic cells (DCs) is considered to be involved in the pathogenesis of ITP.CD70 is transiently and stimul
【机 构】
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昆明医科大学第二附属医院;中国医学科学院血液病医院(血液学研究所) 中国医学科学院血液病医院(血液
【出 处】
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中华医学会第15次全国血栓与止血学术会议
论文部分内容阅读
Background and Aims: Immune thrombocytopenia (ITP) is an autoimmune disorder.Dysfunction of dendritic cells (DCs) is considered to be involved in the pathogenesis of ITP.CD70 is transiently and stimulation-dependently expressed on DCs.There had been reports showing that CD70 was over-expressed in lymphocytes of ITP patients and anti-CD70 antibodies could rectify the over-apoptosis of platelets caused by auto-antibodies in ITP patients.
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