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本论文以方便易得的邻氯硝基苯、单质硫、脂肪胺为原料,在无溶剂无催化剂的条件下实现了苯并噻唑衍生物的绿色合成[1].该反应的显著优点是通过底物内部自身的氧化还原反应完成官能团的转化[2],从而保证了关环反应的顺利完成,反应中不需要额外加入任何的氧化剂或还原剂[3].
以邻氯硝基苯/单质硫/脂肪胺无催化剂无溶剂合成苯并噻唑衍生物
【摘 要】
：
本论文以方便易得的邻氯硝基苯、单质硫、脂肪胺为原料,在无溶剂无催化剂的条件下实现了苯并噻唑衍生物的绿色合成[1].该反应的显著优点是通过底物内部自身的氧化还原反应完成官能团的转化[2],从而保证了关环反应的顺利完成,反应中不需要额外加入任何的氧化剂或还原剂[3].
【机 构】
：
南京工业大学生物与制药工程学院 南京211816
【出 处】
：
中国化学会全国第十一届有机合成化学学术研讨会
【发表日期】
：
2014年5期
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