Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neu

来源 :第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会 | 被引量 : 0次 | 上传用户：UltraSparc

【摘要】

：

Human cytomegalovirus (HCMV) infection of the developing fetus frequently results in major neural developmental damage.In previous studies HCMV was shown to dow

【作者】

：

Xiao-Jun Li Xi-Juan Liu Bo Yang Ya-ru Fu Fei Zhao Zhang-zhou Shen Ling-feng Miao Simon Rayner Stéphane Chavanas Hua Zhu William J.Britt Qiyi Tang Michael A.McVoy Min-Hua Luo

【出处】

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第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会

【发表日期】

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2015年10期

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Human cytomegalovirus (HCMV) infection of the developing fetus frequently results in major neural developmental damage.In previous studies HCMV was shown to down-regulate neural progenitor/stem cell (NPC) markers and induce abnormal differentiation.As Notch signaling plays a vital role in the maintenance of stem cell status and is a switch governing NPC differentiation,the effect of HCMV infection on the Notch signaling pathway in NPCs was investigated.

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Human Cytomegalovirus Infection Dysregulates the Localization and Stability of NICD1 and Jag1 in Neu

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