【摘 要】
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Future nanoscale soft matter design will be guided to a large extent by the teachings of amphiphile (lipid or surfactant) self-assembly.Ordered nanostructured lyotropic liquid crystalline mesophases m
【机 构】
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CSIRO Materials Science and Engineering Bag 10,Clayton,Victoria,3169,Australia
【出 处】
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International Conference on Nanoscience & Technology,China 2
论文部分内容阅读
Future nanoscale soft matter design will be guided to a large extent by the teachings of amphiphile (lipid or surfactant) self-assembly.Ordered nanostructured lyotropic liquid crystalline mesophases may form in select mixtures of amphiphile and solvent.To reproducibly engineer the low energy amphiphile self-assembly of materials for the future, we must first learn the design principles.In this presentation I will discuss the evolution of these design rules and in particular discuss recent key findings regarding (i) what drives amphiphile self-assembly (hydrophobic/solvophobic effect), (ii) what governs the self assembly structures that are formed, and (iii) how can amphiphile self-assembly materials be used to enhance product formulations, including drug delivery vehicles, medical imaging contrast agents, and integral membrane protein crystallisation media [1,2,3].The focus will be on the generation of dilutable lyotropic liquid crystal phases with ordered two-and three-dimensional geometries from amphiphilic small molecules;both bulk and nanoparticulate manifestations of inverse hexagonal and inverse bicontinuous cubic mesophases.The use of high-throughput and combinatorial approaches to accelerate the development of amphiphile self-assembly materials will also be highlighted [2].
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