【摘 要】
：
Introduction: Host remodeling of cell-free, biomaterial-based grafts enables fast integration with the body and is a promising new concept in tissue regeneration.Conventional arterial substitutes such
【机 构】
：
Department of Oral&Maxillofacial Surgery,School of Stomatology,Fourth Military Medical University
【出 处】
：
11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲
论文部分内容阅读
Introduction: Host remodeling of cell-free, biomaterial-based grafts enables fast integration with the body and is a promising new concept in tissue regeneration.Conventional arterial substitutes such as synthetic grafts and tissue engineered blood vessels have sufficient strength so that they can sustain high systolic pressure in the arterial circulation [1,2], however, limited remodeling process, poor compliance and long-term thrombogenesis remain as significant challenges.We hypothesized that remodeling ability of arterial substitutes should be emphasized, and rapid remodeling of a synthetic graft to a neo-artery will likely offer efficient integration with host tissue, a nonthrombogenic lumen, and mechanical properties matching native vessels.
其他文献
目的:抑郁症"突触发生假说"(synaptogenic hypothesis)认为突触功能障碍和抑郁症发生有关.本研究通过运用透射电镜技术观察海马结构中Grey Ⅰ型兴奋性突触形态学改变,为抑郁症"突触发生障碍"假说提供直接的形态学证据.
目的:研究认知正常老年人群不同APOE基因型静息态海马相关记忆网络分布特征,探索APOE基因多态性调控阿尔茨海默病发病风险的神经机制.方法:对129名认知正常老年受试者(ε2携带组36名,ε3纯合子组44名,ε4携带组49名)完成一般资料收集、多维度认知神经心理评估与静息态功能磁共振扫描.采用AFNI软件预处理影像数据并标准化至MNI空间.
目的:败血症及其并发症是导致重症监护区患者死亡的一个主要疾病,约占ICU死亡率的10-50％.由败血症引起的炎症级联反应导致多器官衰竭直至死亡,其中包括败血症脑病.寄居于中枢神经系统的小胶质细胞内固有免疫信号通路的激活不仅见于感染,而且在脑损伤和慢性疾病中也常见.小胶质细胞前体细胞的激活及寄居的小胶质细胞的过度活化需要被抑制,从而避免对脑组织的过度破坏.寻找能够维持小胶质细胞保持静息或活化状态的关
There is now unequivocal evidence that the angiotensin-converting enzyme 2(ACE2)-Ang-(1-7)-Mas axis is a key component of the renin-angiotensin system (RAS) cascade,which is closely correlated with is
The members of high-temperature requirement (HtrA) family are evolutionarily conserved serine proteases that combine a trypsin-like protease domain with at least one PDZ interaction domain.HtrA2,a spe
背景与目的:缺血性脑卒中后小胶质细胞迅速被激活参与脑免疫炎症过程,外周T细胞在缺血24小时内即可浸润至受损脑组织,目前关于小胶质细胞和T细胞在缺血后crosstalk的研究甚少.脑卒中后,脑组织中可溶性FasL(sFasL)的表达有所升高,sFasL具有募集中性粒细胞以及抗凋亡的作用,但其对于T细胞的作用尚不明确.本研究旨在研究缺血性脑卒中后小胶质细胞是否与T细胞具有crosstalk,以及sFa
Background and Objective:It is unclear whether previous statin therapy influences the therapeutic effect of thrombolysis with recombinant tissue plasminogen activator (rtPA) in stroke patients.We aime
目的:卒中已经成为现今我国居民死亡的第一位杀手.国外大型随机临床试验的结果表明,治疗时间窗内应用重组组织型纤溶酶原激活剂(recombinant tissue plasminogen activator,rt-PA)静脉溶栓是改善急性缺血性卒中预后最有效治疗手段.然而临床医生及患者均对溶栓治疗的出血性风险存在较多顾虑,造成溶栓比例偏低.本研究选取我院3年来急性脑梗死(Acute cerebral
目的:探讨奥卡西平治疗耳鸣的临床应用价值.方法:临床收集10例不同程度的耳鸣患者,根据患者的耳鸣程度,给予不同剂量的奥卡西平,在治疗调和8周时,分别进行耳鸣残疾量表评分.结果:10例患者耳鸣程度均有不同程度的好转,治疗前后的耳鸣残疾量表评分具有统计学差异.功能性评分和严重性评分的改变与耳鸣残疾量表评分的改变存在相关关系,而情感评分的改变与其无相关关系.
Nuclear factor of activated T-cells,cytoplasmic 4 (NFATc4),a transcriptional factor,is involved in the control about the flow of genetic information and the modulation of diverse cellular activities.A