多信号通道荧光探针:精准识别单细胞内AP-site

来源 :中国化学会第十二届全国微全分析系统学术会议、第七届全国微纳尺度生物分离分析学术会议、第七届国际微流控学学术论坛 | 被引量 : 0次 | 上传用户:xunitt1
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  AP 位点作为基因组中主要的损伤位点之一,通常呈现出网络化、高速的动态变化,因此准确识别AP 位点异常困难,尤其是在单细胞水平上。
其他文献
INTRODUCTION ZnO nanowires(or nanorods),which possess the characteristics of wide direct bandgap and large exciton binding energy,have been extensive researched and functioned in the past few years.
INTRODUCTION Endotoxin,a liposaccharide,is one of the analytes that requires a highly sensitive detection for medical safety.The Limulus amebocyte lysate(LAL)assay is the most commonly used method for
INTRODUCTION Neurons and cardiac cells exhibit electrical activity,which is usually measured in-vitro using Multi-Electrode-Array(MEA)devices [1].This work proposes a bio-hybrid platform which interfa
INTRODUCTION Electrochemical imaging using a multi-electrode array has used for the various bio-sample evaluations,such as metabolic activity of the cell spheroids,and a neurotransmitter release activ
离子浓差极化(Ion Concentration Polarization,ICP)是伴随着离子选择性输运过程的普遍现象,在电渗析、电镀、电解的诸多应用中都有重要的作用。报告讲述纳米通道中的离子选择性输运产生的离子浓差极化现象如何用于高效生物分子富集、海水淡化、及离子分离等。
In this work,an electrochemiluminescence(ECL)biosensing method for the detection of blood glucose incorporating a paper-based microfluidic sensor and a smartphone is developed.The paper-based microflu
A method for screening of histone deacetylase(HDAC)inhibitors in natural products by using capillary electrophoresis(CE)equipped with laser induced fluorescence(LIF)detection was developed.
传统制备多功能微球的方法有很多,如乳液聚合法,自主装法,喷雾干燥法,模板法等。但是这些方法具有一定的局限性,如难以控制微球的尺寸以及单分散性,微观结构等。
会议
Here,we demonstrate microfluidic devices integrated with nanorod arrays for high-sensitive immunoassays and high-resolution separation of DNA/proteins.Dense arrays of nanorods are fabricated through o