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5. CONDITIONAL KNOCKOUT OF FGF13 IN MURINE HEARTS CAUSES FLECAINIDE-INDUCIBLE VENTRICULAR TACHYARRHYTHM

CONDITIONAL KNOCKOUT OF FGF13 IN MURINE HEARTS CAUSES FLECAINIDE-INDUCIBLE VENTRICULAR TACHYARRHYTHM

来源 :19th Annual Scientific Meeting of the Institute of Cardiovas | 被引量 : 0次 | 上传用户：temp_dl

【摘 要】

：

Aims: Cardiac Na+ channels play critical roles in impulse generation and conduction in ventricular tissue.Fibroblast growth factor homologous factors (FHFs) are essential modulators of Na+ channels an

【作 者】

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C Wang H Tang EQ Wei ZH Wang J Yang YJ Zhang GS Pitt HL Zhang 

【机 构】

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Department of Pharmacology,Hebei Medical University,China

【出 处】

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19th Annual Scientific Meeting of the Institute of Cardiovas

【发表日期】

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2015年9期

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论文部分内容阅读

Aims: Cardiac Na+ channels play critical roles in impulse generation and conduction in ventricular tissue.Fibroblast growth factor homologous factors (FHFs) are essential modulators of Na+ channels and FGF12, the dominant FHFs in human heart, has recently been described as a locus for Brugada Syndrome.

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