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Throughout the development of glycobiology，some polysaccharides such as those found in cordyceps sinensis，cryptoporus polysaccharide，and Cyanobacteria，have been found to have anti-inflammatory properties. Interestingly，the common component of these polysaccharides is mannose.Mannose is a simple hexose sugar with a molecular weight of 180.2，and it has been found to have anti-inflammatory effects.Mannose treatment inhibits the inflammatory reaction in wound healing and decreases leukocytes，especially neutrophils，in wound fluid. Mannose also inhibits the neutrophil oxidative burst，which plays an important role in inflammation. Mannose-6-phosphate，the mannose derivative，has been shown to inhibit adjuvant arthritis and have anti-inflammatory activity in wound healing.