A variant within intron 1 of PTPN22 gene decreases the genetic susceptibility of Ankylosing Spondyli

来源 :2014全球华人遗传学大会暨全国第十三次医学遗传学学术会议 | 被引量 : 0次 | 上传用户:fanrend
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Objective: The protein tyrosine phosphates non-receptor type 22 (PTPN22) were generally accepted as a key factor to maintain immune cellular homeostasis.No association was shown between polymorphisms of PTPN22 and Ankylosing Spondylitis (AS) in Chinese population.We attempted to explore an association between PTPN22 gene and AS in a central south Chinese population.
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