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  5. Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-β/Smad pathway in vascul

Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-β/Smad pathway in vascul

来源 :2016年第一届中国微循环周(中国病理生理学会微循环专业委员会全体会议、世界中医药学会联合会气血专业委员会全体会议、中国 | 被引量 : 0次 | 上传用户：roubaozi320
【摘 要】
：
The study was designed to investigate the role of endogenous sulfur dioxide(SO2)in collagen remodeling and its mechanisms in vascular smooth muscle cells(VSMCs).Overexpression of endogenous SO2 syntha
【作 者】
：
Ya-Qian Huang Zhi-Zhou Shen Qing-Hua Chen Pan Huang Heng Zhang Shuxu Du Bin Geng Chunyu Zhang Kun Li Chao-Shu Tang Jun-Bao Du Hong-Fang Jin 
【机 构】
：
Department of Pediatrics,Peking University First Hospital,Beijing 100034,China
【出 处】
：
2016年第一届中国微循环周(中国病理生理学会微循环专业委员会全体会议、世界中医药学会联合会气血专业委员会全体会议、中国
【发表日期】
：
2016年5期
【关键词】
：
sulfur dioxide collagen remodeling vascular smooth muscle cells transforming gro 
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　　The study was designed to investigate the role of endogenous sulfur dioxide(SO2)in collagen remodeling and its mechanisms in vascular smooth muscle cells(VSMCs).Overexpression of endogenous SO2 synthase aspartate aminotransferase(AAT)1 or 2 increased SO2 levels and inhibited collagen Ⅰ and Ⅲ expressions induced by transforming growth factor(TGF)-β1 in VSMCs.
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