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5. Cornel iridoid glycoside induces autophagy to protect against tau oligomer neurotoxicity induced by

Cornel iridoid glycoside induces autophagy to protect against tau oligomer neurotoxicity induced by

来源 :2019全国老年痴呆与认知障碍相关疾病学术大会 | 被引量 : 0次 | 上传用户：lmd1028

【摘 要】

：

Tau oligomers are the etiologic molecules of Alzheimer disease(AD),and correlate strongly with neuro-nal loss and exhibit neurotoxicity.Recent evidence indicates that small tau oligomers are the most

【作 者】

：

YANG Cui-cui LI Xue-lian ZHANG Li LI Ya-li LI Lin ZHANG Lan 

【机 构】

：

Department of Pharmacy,Xuanwu Hospital of Capital Medical University,Beijing Institute for Brain Dis

【出 处】

：

2019全国老年痴呆与认知障碍相关疾病学术大会

【发表日期】

：

2019年10期

【关键词】

：

cornel iridoid glycoside autophagy tau oligomer glycogen synthase kinase-3β 

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　　Tau oligomers are the etiologic molecules of Alzheimer disease(AD),and correlate strongly with neuro-nal loss and exhibit neurotoxicity.Recent evidence indicates that small tau oligomers are the most relevant toxic aggre- gate species.

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