COPD急性加重期痰曲霉菌阳性患者62例临床特点分析

来源 :2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户：flurryzhang

【摘要】

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【作者】

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温明春臧宁于农徐爱珍魏春华

【机构】

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潍坊哮喘病医院呼吸科潍坊医学院;潍坊哮喘病医院呼吸科

【出处】

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2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议

【发表日期】

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2014年3期

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目的探讨慢性阻塞性肺病(COPD)痰曲霉菌阳性患者的临床特征及早期抗真菌干预的疗效.方法选择潍坊哮喘病医院2013年6月至2014年3月住院,痰培养曲霉菌阳性AECOPD患者62例,列为研究组,选取同期AECOPD患者68例设为观察组,对照分析其易患因素、临床特征,并观察早期即拟诊(宿主因素+临床特征)和临床诊断后(宿主因素+临床特征+微生物学)后抗真菌干预治疗的差异;结果高龄、合并基础疾病、肺功能损害、低血清白蛋白水平、长期使用糖皮质激素和广谱抗生素是引起曲霉菌感染的主要诱因,研究组62例COPD痰培养曲霉菌阳性患者经抗真菌治疗治疗,两组患者CAT评分和mMRC评分(级)明显降低,FEV1％明显升高(均P＜0.05);且早期治疗组患者明显优于临床诊断后治疗的患者.

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COPD急性加重期痰曲霉菌阳性患者62例临床特点分析

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