Pain control in oral surgery is important to both surgeon and patient.Ineffective control of perioperative pain in oral surgery increase patients discomfort,morbidity,anxiety and complication.Pharmacological intervention using non-steroidal anti-inflammatory drugs(NSAIDs)and weak opioids are effective methods for perioperative pain control.In particular,oral administration is safe and convenient.However,variety of NSAIDs are confusing dentist which analgesic is the best selection.Insufficient dose and improper usage of NSAIDs and opioids failed to control perioperative pain due to increasing side effects.To achieve optimal medication with NSAIDs and weak opioids,dentists need to know which oral analgesics are reasonable and effective.WHO pain ladder is a guideline of pain management and Oxford league table of analgesic efficacy reveal intrinsic activity of common oral analgesics.Based on these previous studies,dentists can prescribe optimal oral analgesics for perioperative pain control in oral surgery.