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A new chip to handle liquid dispensation was proposed.We combined nano patterns with plasma treatment to build a regional hydrophilic chip which can obtain a droplets array with just a mere contact with the regent.To demonstrate the application of this liquid dispensation method,this chip was utilized for fast sampling in bio reactions.Droplets of different sizes or different regents were obtained for bio reactions.By combining a gradient generator with this chip,droplets array with concentrations in gradient was generated.High throughput toxic screening of CdSe quantum dots on HL-60 cells was conducted and cell death rates were counted.