Because of the dosage of metakaolin and ash fly had a big impact on the performance optimization of inorganic silicon aluminum polymer, using of metakaolin and ash fly can optimize the pore structure and hydration products of inorganic silicon aluminum polymer paste, how to determine the dosage of metakaolin and ash fly of inorganic silicon aluminum polymer reasonably and directly has become a problem in this research needed to be resolved instantly at hand.The current study investigated the relationship between the amounts of metakaolin and fly ash added and the compressive strength of the inorganic silicon aluminum polymer paste, and then established relevant mathematical model using a quadratic regression quadrature combination design.Previous studies have shown that the addition of 13.56% metakaolin and 3% fly ash would be the optimal plan, and that 57.4 MPa would be the maximum value of the compressive strength of the cement paste of inorganic silicon aluminum polymer that could be obtained.