The inheritance and programming of parental DNA methylomes in vertebrates

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户:OSEric
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5-methylcytosine is a major epigenetic modification that is sometimes called "the fifth nucleotide." However, our knowledge of how offspring inherit the DNA methylome from parents is limited.We generated singlebase resolution DNA methylomes of gametes and early embryo in zebrafish and mouse.
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