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Individual and combined effects of microwave(MW)and alkali pretreatment methods were studied in order to enhance the sludge disintegration and subsequentaerobic digestion of waste activated sludge(WAS).Individual pretreatment with MW(600W-85℃-2min),conventional heating(580W-80℃-12 min)and alkali(1.5gNaOH/L-pH12-30min)was observed to achieve 8.5%,7%and 18%COD solubilization,respectively.However,combined MW-alkali pretreatment synergistically enhanced 20%in sludge solubilization(DSCOD)and achieved 46%COD solubilization as compare to individual MW and alkali pretreatment(8.5%+18%= 26.5%).Moreover batch aerobic digestion study of MW-alkali pretreated sludge revealed 93%and 63%reduction in SCOD and VSS concentration,respectively,at 16 days SRT,thus 20%higher VSS reduction was registered than the control run.