【摘 要】
：
Replication and transcription of influenza virus genome mainly depend on its RNA dependent RNA polymerase (RdRP), composed of the PA, PB1, and PB2 subunits.Alth
【机 构】
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InstituteofBiophysics,Beijing,ChinaSchoolofLifeSciences,TsinghuaUniversity,Beijing,China
【出 处】
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The 9th Asian Biophysics Association Symposium (ABA2015)(第九届
论文部分内容阅读
Replication and transcription of influenza virus genome mainly depend on its RNA dependent RNA polymerase (RdRP), composed of the PA, PB1, and PB2 subunits.Although extensively studied, the underlying mechanism of the RdRP complex is still unclear.Here we report the biochemical characterization of influenza RdRP subcomplex comprising PA, PB1, and N terminus of PB2, which exist as dimer in solution and can assemble into a tetramer state,
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