超声波分散温度诱导碳纳米管上BSA构象变化的光电化学研究

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：kof8697

【摘要】

：

蛋白质作为基因表达产物是生命活动的执行者，其生理功能往往取决于它的分子构象，因此研究蛋白质构象转变具有重要意义.目前许多光物理学手段已用于研究各种物理、化学和环境因素及药物分子对蛋白质构象的影响[1].BSA 是一种生物体内含有两个色氨酸残基(Trp)的无辅助因子运载蛋白，常被用作模型蛋白、分散剂及合成功能材料的模板[2].

【作者】

：

李南希李晓丹李红

【机构】

：

华南师范大学化学与环境学院,510006

【出处】

：

中国化学会第十届全国化学生物学学术会议

【发表日期】

：

2017年10期

【关键词】

：

牛血清白蛋白构象碳纳米管光电化学

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Multivalent DNA nanoblossom for single cell detection

Single cell detection has become particularly important to reveal physiological information of individual cell because there are heterogeneities in all cell populations and even within cell lineages s

会议

Hybridization chain reactionMultivalent bindingDNA nanoblossomSingle cell det

基于Ag+介导的引物延伸反应检测DNA中4mC修饰

4mC 是细菌DNA 中一种重要的表观遗传修饰。金属离子Ag+可以通过与腺嘌呤和胞嘧啶中N 的配位作用稳定碱基错配,形成A-Ag+-C 复合物,但是4mC中N-4 位甲基的引入则会因为位阻效应阻碍该复合物的形成。在Ag+的存在下,DNA 聚合酶延伸胞嘧啶和N4 甲基胞嘧啶至引物与腺嘌呤形成A-Ag+-C 错配的能力不同。

会议

表观遗传修饰N-4甲基胞嘧啶Ag+

Self-assembled supramolecular nanoparticles for targeted tumor imaging and combined chemotherapy

Despite significant advances have been made in cancer treatment,the efficacy of conventional therapy is compromised by severe side effects and drug resistance.

会议

Self-assembled supramolecular nanoparticlesImagingCombined chemotherapyTarget

Zwitterionic Manganes Metal-Organic Frameworks as Potential Magnetic Resonance Contrast Agents

Magnetic resonance imaging(MRI)is a powerful non-invasive medical diagnostic technique.1 It can differentiate abnormalities from normal tissues based on their varied NMR water proton signals.

会议

Magnetic resonance imageMetal-organic frameworksLongitudinal relaxation rates

A Fluorogenic Phosphine-Ester Conjugate for Monitoring Protein S-nitrosylation in Endothelial Cells

As a post-translational modification,protein S-nitrosylation has been increasingly recognized as an important signaling process in vascular physiology and pathology,[1] and its in situ detection would

会议

S-nitrosylationposttranslational modificationfluorescent probeimaging

A Novel Universal Type of MnO2-Mediated On-Off Switch Sensor for Detection of Alkaline Phosphatase a

Because of its unique physicochemical properties and excellent biocompatibility,polydopamine(PDA)has been utilized as a novel platform for biosensing and bioimaging.

会议

DopaminePolydopamineAlkaline phosphatasePesticide

Making Modified Cyclic Peptides Using Enzymes

Cyanobactins are a group of post-translationally modified ribosomal peptides of which the patellamides are the most complex examples.

会议

Molecular probe for measuring proteostasis decline in cells

Maintaining proteostasis is an essential housekeeping function for cell survival.It involves chaperones and degradative pathways to ensure proteins fold correctly and to remove those that are misfolde

会议

Proteostasisprotein foldingneurodegenerative diseasefluorescence

Light-triggered Assembly of Gold Nanoparticles for Tumour Theranostics

Gold nanoparticles(AuNPs)as potent theranostic agents have extensively been studied for photothermal therapy,radiosensitization,and photoacoustic(PA)imaging of cancers.

会议

Gold nanoparticlesLight-triggered assemblyPhotothermal therapyPhotoacoustic i

Investigation of the interactions between the aptamer and Aβ species by single molecule force spectr

Increasing knowledge on the understanding interactions of aptamer with misfolded proteins(including monomer,oligomer and amyloid fibril)is crucial for diagnosis of amyloid diseases.

会议

AptamerMonomerOligomerAmyloid fibrilSingle molecule force spectroscopy

超声波分散温度诱导碳纳米管上BSA构象变化的光电化学研究

与本文相关的学术论文