论文部分内容阅读
We had previously introduced a novel concept wherein recombinantoncolytic viruses (OVs) encoding tumor-associated antigens(termed oncolytic vaccines) could elicit potent anti-tumor immunity while maintaining the ability to infect and replicate within tumor cells.In particular,using the OV as a boostingagent can induce massive secondary expansion of pre-existing tumor-specific memory T cells (Tm).