Protein conjugation systems of autophagy participate in acrosome biogenesis during spermatogenesis

来源 :中国细胞生物学学会2013年全国学术大会 | 被引量 : 0次 | 上传用户:yulekan
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Acrosome is a specialized organelle which covers the anterior part of sperm nuclear and plays essential role in sperm-egg fusion.Defect of acrosome biogenesis results in severe fertility disorder called globozoospermia.Here we reported that deletion of Atg7 in germ cells caused male mice infertile with a phenotype resembling globozoospermia.
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