【摘 要】
：
TLR agonists can induce the maturation of dendritc cells and enhance their roles in presenting tumor antigens.ProTα is a small highly acidic polypeptide of 109 amino acid residues in humans, and in me
【机 构】
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College of Pharmaceutical Scicences, Soochow University, 199 Renai Road, Suzhou Industrial Park, Jia
【出 处】
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2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会
论文部分内容阅读
TLR agonists can induce the maturation of dendritc cells and enhance their roles in presenting tumor antigens.ProTα is a small highly acidic polypeptide of 109 amino acid residues in humans, and in melanoma and colorectal cancer patients, proTα stimulated the production of the proinflammatory cytokines IL-1β and TNF-α, reduced the secretion of TGF-β and prostaglandin E2 and consequently normalized peripheral blood monocyte and lymphokine-activated killer cell disorders.
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