Purpose:Osteoarthritis(OA)is a common cause of disability worldwide.It leads to social,psychological,and economical burdens to patients and incur significant financial consequences.In order to develop scientific evidence based tai chi or other exercise intervention programs for OA management,more research in joint biomechanics of the OA patients and tai chi movements biomechanics should be conducted.Methods:This article reviewed the biomechanics and pathomechanisms of OA,the mechanical nature of OA onset and progression,the biomechanical interventions for its treatment and rehabilitation and research on tai chi biomechanics and on its effects on lower-limb OA management.Results and conclusion:OA is a disease of the entire joint;its multifactorial etiology includes increased mechanical stress,ligament derangement,cartilage degradation,subchondral bone change,and muscular impairment.Although the exact cause of OA remains unknown,evidence indicates that altered loading mechanisms and increased mechanical forces on weight-bearing joints significantly contribute to OA onset and progression.