Detection of a-Fetoprotein and Glypican-3 mRNAs in the Peripheral Blood of Hepatocellular Carcinoma

来源 :2013第六届世界癌症大会 | 被引量 : 0次 | 上传用户:sb871697914
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  This work aimed to investigate the correlation of the expression of a-fetoprotein (AFP) and glypican3 (GPC3) mRNAs in the peripheral blood with primary hepatocellular carcinoma (HCC) and HCC metastasis by using multiple fuorescence quantitative reverse transcriptase-polymerase chain reaction (FQ-RT-PCR).Peripheral blood samples from 100 patients with HCC were collected.The positive expression rates of AFP mRNA of HCC, hepatitis B, and cirrhosis patients were 56, 5, and 10%,respectively.AFP mRNA was not detected in healthy subjects, hepatic hemangioma, or hepatic metastasis patients samples.
其他文献
The development of severe metabolic acidosis in seriously ill patients is often accompanied by multi-organ dysfunction and an increase in morbidity and mortality.Current acid-base correction with sodi
会议
Experimental studies reveal that the pathogenesis of neurogenic inflammation involves an activation of spinal cord GABAergicinterneuronal circuits where action potentials are generated and then propag
会议
Inflammation in the central nervous system (CNS) is a complex process with a high social and economic irnpact worldwide.Currently there is no effective therapy for prevention and treatment of CNS infl
会议
One of the most common applications of acupuncture is for various kinds of pain.However, its mechanisms remain partly understood particularly for neuropathic pain.Since there is a cyclooxygenase (COX)
会议
LHRH receptors represent a nearly ideal target for personalized medicine approach.LHRH receptors are according to literature expressed in human cancer tissues (e.g.breast cancer > 60 % and endometrial
会议
Vulvar Cancer affects approximately 3000-4000 women in the United States yearly.It makes up approximately 4% of the female genital cancers reported in the U.S.per year.Vulvar reconstruction is an inte
会议
Endometrial cancer is one of the most common cancer of the female genital tract, with endometrioid (type l) and serous (type 2) being the most common cell types.These tumor entities differ with respec
会议
Gastrointestinal tract acid-446 (GTA-446) is a long-chain polyunsaturated fatty acid present in the serum.A reduction of GTA-446 levels in colorectal cancer (CRC) patients has been reported across sev
会议
Circulating tumor cells (CTCs) are malignant cells found in the peripheral blood of patients with solid tumors.Although this phenomenon was recognized more than a century ago, the very low number of C
会议
The entity of circulating tumor cells (CTCs) has become a very interesting topic and entity for scientists and clinicians that are involved with the area of cancer.Since this entity is generated durin
会议