【摘 要】
：
PTEN is one of the most frequently mutated tumor suppressors in human cancer.While its function in tumor suppression is well established,its relationship to anti-microbial immunity remains unknown.Her
【机 构】
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State Key Laboratory of Virology and Modem Virology Research Center,College of Life Sciences,Wuhan U
【出 处】
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第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会
论文部分内容阅读
PTEN is one of the most frequently mutated tumor suppressors in human cancer.While its function in tumor suppression is well established,its relationship to anti-microbial immunity remains unknown.Here we show that PTEN plays a pivotal role in type Ⅰ interferon(IFN)induction,the hallmark of antiviral innate immunity,which is independent of PI3K/Akt pathway.
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