目前放射治疗肺癌的疗效很低,最近木村报告,其5年生存率为7.5％,也有报告为7～8.7％之间。放疗之所以失败,除发生远隔转移外,还由于肿瘤内存在乏氧细胞之故(因为这种细胞对射线有很强的抵抗性)。为此,人们除进行高压氧仓内放疗和高LET照射(快中子或负π介子等)研究外,第三条途径的研究是寻找增加对乏氧细胞有放射敏感性而不影响氧合细胞的放射敏感性的增敏剂,近年来报告颇多。本观察的目的是从中药制剂中探寻经济简便的放射增敏剂,以提高晚期肺癌的放疗效果。现将用0.25％莪术油(以下简称莪术油)增敏放射治疗晚期肺癌病人(Ⅲ期6例、Ⅳ期6例)的临床观察结果,初步小结如下: At present, the efficacy of radiation therapy for lung cancer is very low. Kimura recently reported that the 5-year survival rate was 7.5%, and it was reported to be between 7 and 8.7%. The failure of radiotherapy, in addition to distant metastases, also results from the presence of hypoxic cells in the tumor (because the cells are very resistant to radiation). For this reason, in addition to conducting hyperbaric oxygen chamber radiation therapy and high LET irradiation (fast neutrons or negative π mesons, etc.), the third route is to search for increased radiosensitivity to hypoxic cells without affecting oxygenation. Radiosensitivity sensitizers for cells have been reported in recent years. The purpose of this observation is to explore economically convenient radiosensitizers from traditional Chinese medicine preparations to improve the efficacy of radiotherapy for advanced lung cancer. The clinical observation results of sensitized radiotherapy with 0.25% curcuma oil (hereinafter referred to as curcuma oil) in patients with advanced lung cancer (6 in stage III and 6 in stage IV) are summarized below. The preliminary summary is as follows: