The Drosophila F-box protein dSkp2 regulates cell proliferation through targeting Dacapo for degrada

来源 :2012全国发育生物学大会 | 被引量 : 0次 | 上传用户:Ryan
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  Cell cycle progression is controlled by a complex regulatory network consisting of interacting positive and negative factors.In humans, the positive regulator Skp2, an F-box protein, has been a subject of intense investigations in part because of its oncogenic activities.By contrast, the molecular and developmental functions of its Drosophila homologue, dSkp2, remain poorly understood and controversial.
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