Cancer Risk Estimation in Chinese Medical X-ray Workers

来源 :首届全球华人辐射研究大会 | 被引量 : 0次 | 上传用户:syhrgl
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  Purpose: To make a lifetime cancer risk projection on Chinese medical X-ray workers.Materials and method: Based on pooled data of Chinese medical X-ray workers and a comparison cohort, we obtained sex-, organ-and age-specific baseline cancer incidence rates for Chinese medical X-ray workers.And based on 2000 census mortality data we obtained sex-and age-specific life tables.Then we applied cancer rates, life tables, and exposure history of Chinese medical X-ray workers to the latest cancer risk projection models to estimate baseline cancer cases and radiation related cancer cases for lifetime and 1996 or later for leukemia and cancers of liver, stomach, thyroid and female breast.Results: We obtained sex-, organ-and age-specific baseline cancer incidence rate for Chinese medical X -ray workers.Our main results is that among estimates for cancer sites we selected in the present study, cancers of female breast is the most common form of cancer for lifetime excess cancer and future excess cancer, followed by stomach cancer.And stomach cancer is the most common type of cancer for future baseline caner, followed by liver cancer.From estimates of future excess cancer and future total cancer, we could see that radiation related female breast cancers accounting for 62% (39%-76% for 90% uncertainty range) in future total breast cancer, followed by thyroid cancer for which cancer radiation related cancers occupy 33% (0%-55% for 90% uncertainty range) of future total thyroid cancer.Conclusions: Based on exposure history and cancer cases occurred before January 1st, 1996 among Chinese medical X-ray workers, it suggested that there is dose-response relationship for this cohort and we projected that there will be notable baseline or radiation related cancer cases for leukemia and cancer of liver, stomach, thyroid, and female breast after last follow up.
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