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  5. Downregulation of Selenium-binding Protein 1 is associated with Human Bronchial Epithelial Carcinoge

Downregulation of Selenium-binding Protein 1 is associated with Human Bronchial Epithelial Carcinoge

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：deansam
【摘 要】
：
Human lung squamous cell cancer (LSCC) is one of the leading causes of death in China and worldwide.To analyze altered proteinexpression in human bronchial epithelial carcinogenic process and discover
【作 者】
：
Gu-Qing Zeng Pang-Fei Zhang Feng-Lei Yu Cui Li Hong Yi Mao-Yu Li Zhi-Qiang Xiao 
【机 构】
：
Department of General Surgery and Operative Surgery,School of Medicine,University of South China,Hen
【出 处】
：
第八届中国蛋白质组学大会
【发表日期】
：
2013年11期
【关键词】
：
SELENBP1 LSCC early detection prognosis iTRAQ 
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Human lung squamous cell cancer (LSCC) is one of the leading causes of death in China and worldwide.To analyze altered proteinexpression in human bronchial epithelial carcinogenic process and discover novel potential biomarkers for early detection andprognosis in LSCC,iTRAQ-tagging combined with 2D LC-MS/MS analysis was used to identify differentially expressed proteins inhuman bronchial epithelial carcinogenic process using laser capture microdissection-purified normal bronchial epithelium (NBE),squamous metaplasia (SM),atypical hyperplasia (AH),carcinoma in situ (CIS) and invasive LSCC.
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