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Objectives:Candida albicans is the most common virulent species in human stomatitis.It is frequently seen in patients who wear removable partial dentures,cases who have AIDS and immunodeficiency.The resistance to fungicides of most genus is becoming an increasingly problem,which is worthy of our attention.Epigallocatechin gallate(EGCG)is an effective constituent of tea polyphenol.In this study,EGCG was detected as potential antifungal agent against Candida albicans.