MHC class Ⅰ (MHC Ⅰ) antigen presentation of exogenous antigens (so called "cross presentation") is a central mechanism of CD8+ cytotoxic T lymphocyte (CTL) responses essentially for successful vaccine
In this sdudy we use attenuated cold-adapted influenza vaccine strains as a platform to express fitted RSV F protein and antibody epitopes.And intranasally immunized 6-8 week female BALB/c mice to eva
Introduction: Hepatitis C virus (HCV) vaccine candidates based on viral envelope glycoprotein E2 have shown notable effects on triggering protective immune responses.
Objective: Cystic echinococcosis (CE), also known as hydatidosis, is a zoonotic parasitic disease with a high incidence in Xinjiang.CE is caused by parasitic larvae of Echinococcus granulosus (Eg) in
Background: Five human infections were caused by avian-origin influenza A (H7N9) virus in Nanchangcity during H7N9 outbreak in 2013.Objective: To understand the dynamic profiles of antibody response t
研究目的 : Whether and how type Ⅰ interferon plays the role in the anti-MHV-68 effect of IFN-γ.研究方法 : We detected the expression and production of IFN-α/β by RT-qPCR and ELISA respectively, and the expres
Since the northern pig-tailed macaque (Macaca leonina) has been divided from the pig-tailed macaques group and identified as an independent species of Old World m, we previously found that PBMCs from
Introduction: Staphylococcus aureus (S.aureus) is an opportunistic bacterial pathogen responsible for a diverse spectrum of human diseases.Globally, it is a leading cause of nosocomial and community a
Objective: A novel avian influenza virus H7N9 infection occurred among human populations since 2013.Although the lack of sustained human-to-human transmission limited the epidemics caused by H7N9, the