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The soybean mosaic virus (SMV)-soybean interaction is complex of virus-plant interactions.To assess transcriptional changes in soybean plants infected with soybean mosaic virus (SMV), the soybean leaf was sam pled at 1, 7, 14 days post-inoculation (p.i.) by soybean mosaic virus induced and Phosphate buffer inoculation, respectively and subjected to transcriptome analysis through Illumina sequencing technology.