Nucleophosmin as a Novel Target for Anti-cancer Therapy: The Use and Underlying Molecular Basis

来源 :2014第七届世界癌症大会 | 被引量 : 0次 | 上传用户:xiaohan191420
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  Evading apoptosis is pivotal in both of carcinogenesis and resistance to anti-cancer therapy.We investigated the molecules and pathways of death evasion in human hepatoma cells byinduction of cellular hormetic responsesand identified nucleophosmin (NPM) playing a crucial role to counteract death induction.
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