Hepatitis C virus and its protein NS4B activates cancer-related STAT3 pathway by endoplasmic reticul

来源 :第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会 | 被引量 : 0次 | 上传用户:fzy321
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  Oxidative stress has been reported to induce the activation of signal transducer and activator of transcription 3(STAT3),which plays an important role in hepatocellular carcinoma(HCC).We have previously reported that hepatitis C virus(HCV)and its protein NS4B induces the production of reactive oxygen species(ROS)by endoplasmic reticulum overload response(EOR)in human hepatocytes.
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